Drizzt Do'Urden had followed a line of precepts based upon discipline and ultimate optimism. He fought for a better world because he believed that a better world could and would be made. He had never held any illusions that he would change the world, of course, or even a substantial portion of it, but he always held strongly that fighting to better just his own little pocket of the world was a worthwhile cause.
The researchers looked deeper into these observations, in hopes of gaining insight into the mechanisms underlying the high evolutionary rate and extraordinary immunologic plasticity of influenza HA. They probed in more detail the precise codons that are used by the virus to encode the influenza HA1 protein. The discriminated between codons on the basis of volatility. Each three-nucleotide codon is related by a single nucleotide change to nine 'mutational neighbours.' Of those nine mutations, some proportion change the codon to a synonymous codon and some change it to a nonsynonymous one, which directs the incorporation of a different amino acid into the protein. More volatile codons are those for which a larger proportion of those nine mutational neighbours encode an amino acid change. The use of particular codons in a gene at a frequency that is disproportionate to their random selection for encoding a chosen amino acid is termed codon bias. Such bias is common and is influenced by many factors, but here the collaborators found strong evidence for codon bias that was particular for and restricted to the amino acids making up the HA1 epitopes. Remarkably, they observed that influenza employs a disproportionate number of volatile codons in its epitope-coding sequences. There was a bias for the use of codons that had the fewest synonymous mutational neighbours. In other words, influenza HA1 appears to have optimized the speed with which it can change amino acids in its epitopes. Amino acid changes can arise from fewer mutational events. The antibody combining regions are optimized to use codons that have a greater likelihood to undergo nonsynonymous single nucleotide substitutions : they are optimized for rapid evolution.
“As the first server-based, 'all-in-one' communications software application system, CIC brings with it a long-standing reputation for innovation. With the latest version offering dramatic increases in scalability, along with key performance optimization and enterprise messaging enhancements, CIC continues to lead the market. This innovation, backed by more than 10 years of development experience and over 2,000 global customers, makes CIC truly deserving of our Product of the Year Award.”
When we sacrifice our own well-being in the hopes that our sacrifice will help someone else, we just get two people who are living sub-optimal lives. Here's the truth: Getting sick does not help those who are suffering of illness. Being sad does nothing to pull someone out of their own depression. And being hungry doesn't feed the starving. The universe simply doesn't work that way.
The faith in an afterlife, however much our reason ridicules it, very modestly extends our faith that each moment of our consciousness will be followed by another - that a coherent matrix has been prepared for this precious self of ours. The guarantee that our self enjoys an intended relation to the outer world is most, if not all, of what we ask from religion. God is the self projected onto reality by our natural and necessary optimism. He is the not-me personified.
Thinking outside the box only works if you know everything inside it. Don’t compare your chapter 1 to someone else’s chapter 20. That’s the biggest mistake young entrepreneurs do and end up getting disappointed. The ones you call conventional are the business models, which have been optimized and modified at various stages over a long period of time. You need to work hard and be a bit more patient.
In The Inhuman... Lyotard, like Weber, reminds us of the distinction between technological development and 'human' progress. He argues, in particular, that the development of technology, or 'techno-science', is driven by the quest for maximum efficiency and performance, and as such leads to the emergence of new 'inhuman' (technological) forms of control rather than to the emancipation of 'humanity'. Lyotard reasserts the instrumental nature of the modern system, arguing that 'All technology ... is an artefact allowing its users to stock more information, to improve their competence and optimize their performances'. In this view, techno-science may be seen to stand against all instances of the unknown, including the aporia of the future anterior, and thus to have little respect for forms which are different or other to itself. This is compounded by the fact that technological development is intimately connected to the drive for profit. Lyotard proposes that this directs the production of knowledge and conditions the nature of knowledge itself, for information, itself a commodity, is increasingly produced in differentiated, digestible forms ('bits') for ease of mass exchange, transmission and consumption, and with the aim of enabling the optimal performance of the global system.
“For several years now, search engine marketing and optimization has dominated online marketing, and this data shows why: it's far more effective at converting visitors into buyers than most other acquisition sources taken as a whole. But as this data also shows, the best conversion rate still comes from good old fashioned branding and customer loyalty, where visitors either bookmark your site or type your URL directly into the address bar.”
“The availability of mission critical information systems is often tied directly to business performance or revenue. When there is unplanned downtime due to a system crash during primary service hours, the result can have a immense impact on an organization's financial stability. As a result, fault tolerant servers are becoming more widely accepted as a strong alternative to help organizations minimize risk, meet regulatory requirements optimize network resources and minimize loss of profits, customers, or productivity.”
When we understand who we are, and how our realities work, we can choose more consciously to shape our lives in an optimal way. Knowledge of oneself is the very key to a happy life. Happiness is not something outside of our own consciousness that needs to be earned, and achieved. It is a choice that needs to be supported by positive actions. It is not enough to say that we want to be happy. Our desire of happiness, love and peace, needs to be supported by our state of being.